Skardal Biofabrication Lab

Skardal Biofabrication Lab

About the Lab

Our research program focuses on the design and implementation of extracellular matrix-inspired hydrogel biomaterials for the biofabrication of tissue and tumor organoids, organ-on-a-chip systems, and cancer-on-a-chip systems for drug screening, disease modeling, and personalized medicine. Our team’s work has broad applicability across tissue types and diseases but has focused primarily in development of cancer models and recently neural models. Our biomaterial systems are largely hyaluronic acid-based with additional custom ECM component addons, synthetically modified in the lab. These are often combined with microfluidic devices for fluid handling capabilities. In particular, we have a significant interest in patient biospecimen-derived models that can facilitate and improve current precision medicine and precision oncology efforts in the clinic.

Accordions

Related News

Ohio State Lab Members

Hema Sivakumar, MS
Hema Sivakumar, MS
Research Associate
Thomas Depalma, BSc
Thomas Depalma, BSc
PhD Student, Biomedical Engineering
Kylie Nairon, BSc
Kylie Nairon, BSc
PhD Student, Biomedical Engineering

Wake Forest School of Medicine Lab Members

Andrea Mazzocchi, BSc
Andrea Mazzocchi, BSc
PhD Student, Biomedical Engineering
Steven Forsythe, MS
Steven Forsythe, MS
PhD Student, Cancer Biology
Shiny Rajan, MS
Shiny Rajan, MS
PhD Student, Biomedical Engineering
Casey Clark, BSc
Casey Clark, BSc
PhD Student, Biomedical Engineering

Former Lab Members

Julio Aleman, BSc
Julio Aleman, BSc
Current: PhD Student, University of Pittsburgh
Hesh Devarasetty, PhD
Hesh Devarasetty, PhD
Current: Postdoctoral Fellow, Wake Forest Institute for Regenerative Medicine
Connor Huntwork, BSc
Connor Huntwork, BSc
Current: PhD Student, University of Wisconsin
News
Undergraduate Research Spotlight: Kennedy Hughes
Hughes works in the Skardal Biofabrication Lab where they use engineering tools to create complex 3D models of human disease. Her work in the lab has allowed her to build...
2023 Pelotonia Annual Report highlights Skardal's bioprinted organoids
Aleksander Skardal , Ph.D., Associate Professor in BME and member of The Ohio State University Comprehensive Cancer Center (OSUCCC) was recently featured in the 2023 Pelotonia...
Ohio State researchers evaluating one of AstraZeneca’s cancer therapy candidates
Biomedical Engineering Associate Professor Aleksander Skardal leads a multidisciplinary team of Ohio State University researchers who have entered into a research collaboration...